Acute and Critical Care

Case Report

Pulmonary
Lung Transplantation for Chronic Humidifier Disinfectant-Associated Lung Injury: Won-Young Kim, So-Woon Kim, Kyung-Wook Jo, Sae Hoon Choi, Hyung Ryul Kim, Yong-Hee Kim, Dong Kwan Kim, Seung-Il Park, Sang-Bum Hong; Korean J Crit Care Med. 2016;31(2):146-151. Published online May 31, 2016; DOI: https://doi.org/10.4266/kjccm.2016.31.2.146

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In the spring of 2011, a cluster of lung injuries caused by humidifier disinfectant (HD) usage were reported in Korea. Many patients required mechanical ventilation, extracorporeal membrane oxygenation, and even lung transplantation (LTPL). However, the long-term course of HD-associated lung injury remains unclear because the majority of survivors recovered normal lung function. Here we report a 33-year-old woman who underwent LTPL approximately four years after severe HD-associated lung injury. The patient was initially admitted to the intensive care unit and was supported by a high-flow nasal cannula. Although she had been discharged, she was recurrently admitted to our hospital due to progressive lung fibrosis and a persistent decline in lung function. Finally, sequential double LTPL was successfully performed, and the patient’s clinical and radiological findings showed significant improvement. Therefore, we conclude that LTPL can be a therapeutic option for patients with chronic inhalation injury.

Citations

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Humidifier Disinfectant-Associated Lung Injury: Six Years after the Tragic Event
Won-Young Kim, Sang-Bum Hong
Tuberculosis and Respiratory Diseases.2017; 80(4): 351. CrossRef

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