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Letter to the Editor
- Pulmonary
- Septic shock due to invasive pulmonary aspergillosis without conventional risk factors
- Kyung Eun Shin, Shinhee Park, Ae-Rin Baek
- Acute Crit Care. 2023;38(2):238-241. Published online May 25, 2023
- DOI: https://doi.org/10.4266/acc.2023.00437
- 1,395 View
- 69 Download
Original Article
- Infection
- In-hospital mortality prediction using frailty scale and severity score in elderly patients with severe COVID-19
- Yong Sub Na, Jin Hyoung Kim, Moon Seong Baek, Won-Young Kim, Ae-Rin Baek, Bo young Lee, Gil Myeong Seong, Song-I Lee
- Acute Crit Care. 2022;37(3):303-311. Published online July 5, 2022
- DOI: https://doi.org/10.4266/acc.2022.00017
- 4,877 View
- 226 Download
- 7 Web of Science
- 8 Crossref
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Abstract
PDF - Background
Elderly patients with coronavirus disease 2019 (COVID-19) have a high disease severity and mortality. However, the use of the frailty scale and severity score to predict in-hospital mortality in the elderly is not well established. Therefore, in this study, we investigated the use of these scores in COVID-19 cases in the elderly.
Methods
This multicenter retrospective study included severe COVID-19 patients admitted to seven hospitals in Republic of Korea from February 2020 to February 2021. We evaluated patients’ Acute Physiology and Chronic Health Evaluation (APACHE) II score; confusion, urea nitrogen, respiratory rate, blood pressure, 65 years of age and older (CURB-65) score; modified early warning score (MEWS); Sequential Organ Failure Assessment (SOFA) score; clinical frailty scale (CFS) score; and Charlson comorbidity index (CCI). We evaluated the predictive value using receiver operating characteristic (ROC) curve analysis.
Results
The study included 318 elderly patients with severe COVID-19 of whom 237 (74.5%) were survivors and 81 (25.5%) were non-survivors. The non-survivor group was older and had more comorbidities than the survivor group. The CFS, CCI, APACHE II, SOFA, CURB-65, and MEWS scores were higher in the non-survivor group than in the survivor group. When analyzed using the ROC curve, SOFA score showed the best performance in predicting the prognosis of elderly patients (area under the curve=0.766, P<0.001). CFS and SOFA scores were associated with in-hospital mortality in the multivariate analysis.
Conclusions
The SOFA score is an efficient tool for assessing in-hospital mortality in elderly patients with severe COVID-19. -
Citations
Citations to this article as recorded by
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Vijay Sundarsingh, R. Manoj Kumar, Manjunath Kulkarni, Debasis Pradhan, Pramela Renisha Rodrigues, Nishanth Baliga, Mamata Prasad, Pooja Yadav, Monish Thomas, Tania Eltrida Pinto
Journal of Critical Care.2025; 85: 154930. CrossRef - Risk factors for progressing to critical illness in patients with hospital-acquired COVID-19
Kyung-Eui Lee, Jinwoo Lee, Sang-Min Lee, Hong Yeul Lee
The Korean Journal of Internal Medicine.2024; 39(3): 477. CrossRef - Omicron, Long-COVID, and the Safety of Elective Surgery for Adults and Children: Joint Guidance from the Therapeutics and Guidelines Committee of the Surgical Infection Society and the Surgery Strategic Clinical Network, Alberta Health Services
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Surgical Infections.2023; 24(1): 6. CrossRef - Evaluation of risk scores as predictors of mortality and hospital length of stay for older COVID‐19 patients
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AGING MEDICINE.2023; 6(1): 56. CrossRef - Atypical presentation of COVID-19 in older patients is associated with frailty but not with adverse outcomes
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European Geriatric Medicine.2023;[Epub] CrossRef - Neurological Manifestations and Complications of the Central Nervous System as Risk Factors and Predictors of Mortality in Patients Hospitalized with COVID-19: A Cohort Study
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Journal of Clinical Medicine.2023; 12(12): 4065. CrossRef - Modified Early Warning Score: Clinical Deterioration of Mexican Patients Hospitalized with COVID-19 and Chronic Disease
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Healthcare.2023; 11(19): 2654. CrossRef - Risk Factors and Predictive Model for Mortality of Hospitalized COVID-19 Elderly Patients from a Tertiary Care Hospital in Thailand
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Medicines.2023; 10(11): 59. CrossRef
- Quadriceps Muscle Layer Thickness and its association with frailty in critically ill patients: A prospective observational study
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