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Alcohol use disorder in the intensive care unit a highly morbid condition, but chemical dependency discussion improves outcomes
Kristin Colling, Alexandra K. Kraft, Melissa L. Harry
Acute Crit Care. 2023;38(1):122-133.   Published online January 10, 2023
DOI: https://doi.org/10.4266/acc.2022.00584
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AbstractAbstract PDF
Background
Alcohol use disorders (AUD) are common in patients admitted to intensive care units (ICU) and increase the risk for worse outcomes. In this study, we describe factors associated with patient mortality after ICU admission and the effect of chemical dependency (CD) counseling on outcomes in the year following ICU admission. Methods: We retrospectively reviewed patient demographics, hospital data, and documentation of CD counseling by medical providers for all ICU patients with AUD admitted to our institution between January 2017 and March 2019. Primary outcomes were in-hospital and 1-year mortality. Results: Of the 527 patients with AUD requiring ICU care, median age was 56 years (range, 18–86). Both in-hospital (12%) and 1-year mortality rates (27%) were high. Rural patients, comorbidities, older age, need for mechanical ventilation, and complications were associated with increased risk of in-hospital and 1-year mortality. CD counseling was documented for 73% of patients, and 50% of these patients accepted alcohol treatment or resources prior to discharge. CD evaluation and acceptance was associated with a significantly decreased rate of readmission for liver or alcohol-related issues (36% vs. 58%; odds ratio [OR], 0.41; 95% confidence interval [CI], 0.27–0.61) and 1-year mortality (7% vs. 19.5%; OR, 0.32; 95% CI, 0.16–0.64). CD evaluation alone, regardless of patient acceptance, was associated with a significantly decreased 1-year post-discharge mortality rate (12% vs. 23%; OR, 0.44; 95% CI, 0.25–0.77). Conclusions: ICU patients with AUD had high in-hospital and 1-year mortality. CD evaluation, regardless of patient acceptance, was associated with a significant decrease in 1-year mortality

Citations

Citations to this article as recorded by  
  • Identifying excessive chronic alcohol use with phosphatidylethanol in patients with suspected severe injury-results from the IDART study
    Benedicte M Jørgenrud, Camilla C Bråthen, Jo Steinson Stenehjem, Thomas Kristiansen, Leiv Arne Rosseland, Stig Tore Bogstrand
    Alcohol and Alcoholism.2024;[Epub]     CrossRef

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