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Original Article
Nursing
Early postoperative 6-minute walk test in cardiac surgery patients: an observational study assessing safety, feasibility, and predictors of completion in India
Prasanth Jayaraman, Puvaneswari Kanagaraj, Shrinivas Hittalamani
Acute Crit Care. 2025;40(4):614-626.   Published online November 28, 2025
DOI: https://doi.org/10.4266/acc.000050
  • 1,625 View
  • 76 Download
AbstractAbstract PDFSupplementary Material
Background
Early mobilization after cardiac surgery is crucial for enhancing recovery, minimizing complications, and promoting timely discharge. The 6-minute walk test (6MWT) is a validated measure of functional capacity; however, its use during the early postoperative period—particularly in Intensive care Unit (ICU) settings in India—remains underexplored. This study assesses the safety, feasibility, and functional performance outcomes of the 6MWT administered on postoperative days (PODs) 2 to 4 and identifies factors associated with test completion.
Methods
A cohort-based observational study was conducted in a tertiary care ICU between June and September 2021. In total, 150 cardiac surgery patients aged 30–70 years were enrolled. Inclusion required hemodynamic stability, no vasopressor/inotropic support, and ambulation from POD 2. The 6MWT was administered per the American Thoracic Society guidelines. Clinical, demographic, and physiological parameters were recorded and analyzed using descriptive statistics, paired t-tests, and regression analyses.
Results
Of the 150 patients, 140 completed the test. The mean age was 52±14 years, and 75% of participants were male. Mean walking distances improved from 78.14 m (21.7% of predicted) on POD 2 to 193.51 m (53.75%) on POD 4. Completion rates increased from 40.0% to 99.2%. Physiological responses remained within safe limits, and no serious adverse events occurred. The regression analyses identified education, diet, and oxygen saturation as positive predictors and comorbidities, being female, oxygen use, and physical occupation as negative predictors.
Conclusions
The 6MWT is a safe, feasible, and informative tool for assessing early functional recovery in stable post-cardiac surgery ICU patients to aid individualized rehabilitation and discharge planning.
Review Article
Trauma
Mobilization phases in traumatic brain injury
Tommy Alfandy Nazwar, Ivan Triangto, Gutama Arya Pringga, Farhad Bal’afif, Donny Wisnu Wardana
Acute Crit Care. 2023;38(3):261-270.   Published online August 1, 2023
DOI: https://doi.org/10.4266/acc.2023.00640
  • 21,616 View
  • 550 Download
  • 7 Web of Science
  • 8 Crossref
AbstractAbstract PDF
Mobilization in traumatic brain injury (TBI) have shown the improvement of length of stay, infection, long term weakness, and disability. Primary damage as a result of trauma’s direct effect (skull fracture, hematoma, contusion, laceration, and nerve damage) and secondary damage caused by trauma’s indirect effect (microvasculature damage and pro-inflammatory cytokine) result in reduced tissue perfusion & edema. These can be facilitated through mobilization, but several precautions must be recognized as mobilization itself may further deteriorate patient’s condition. Very few studies have discussed in detail regarding mobilizing patients in TBI cases. Therefore, the scope of this review covers the detail of physiological effects, guideline, precautions, and technique of mobilization in patients with TBI.

Citations

Citations to this article as recorded by  
  • Benchmarking mobilization practice and functional outcomes in traumatic brain injury patients admitted to the intensive care unit: a three-year service evaluation
    Fiona Howroyd, James Hodson, Anne Preece, Tammy Lea, Samantha Rooney, Hon Sing Geoffrey Wu, Simran Rahania, Fang Gao Smith, Tonny Veenith, Niharika A. Duggal, Zubair Ahmed, Jonathan Weblin
    Frontiers in Neurology.2026;[Epub]     CrossRef
  • The Impact of a Prior Traumatic Brain Injury and Injury Characteristics on Frailty in the Canadian Longitudinal Study on Aging
    Molly K. Courish, Myles W. O’Brien, Madeline E. Shivgulam, Emily E. MacDonald, Said Mekari, Olga Theou
    Archives of Physical Medicine and Rehabilitation.2026;[Epub]     CrossRef
  • Reversing Persistent PTEN Activation after Traumatic Brain Injury Fuels Long‐Term Axonal Regeneration via Akt/mTORC1 Signaling Cascade
    Ziyu Shi, Leilei Mao, Shuning Chen, Zhuoying Du, Jiakun Xiang, Minghong Shi, Yana Wang, Yuqing Wang, Xingdong Chen, Zhi‐Xiang Xu, Yanqin Gao
    Advanced Science.2025;[Epub]     CrossRef
  • Falls in a single brain rehabilitation center: a 3-year retrospective chart review
    Yoo Jin Choo, Jun Sung Moon, Gun Woo Lee, Wook-Tae Park, Min Cheol Chang
    Frontiers in Neurology.2025;[Epub]     CrossRef
  • Effects of using conventional assistive devices on spatiotemporal gait parameters of adults with neurological disorders: A systematic review protocol
    Jordana de Paula Magalhães, Sheridan Ayessa Ferreira de Brito, Merrill Landers, Aline Alvim Scianni, Poliana do Amaral Yamaguchi Benfica, Carolina Luisa de Almeida Soares, Christina Danielli Coelho de Morais Faria, Anne E. Martin
    PLOS ONE.2025; 20(4): e0321019.     CrossRef
  • Impact of Early Mobilisation on the Clinical Outcomes of Patients With Traumatic Brain Injury
    Fei Xia, Caiyun Li, Yiwen Liu
    Nursing in Critical Care.2025;[Epub]     CrossRef
  • Acute orthostatic responses during early mobilisation of patients with acquired brain injury - Innowalk pro versus standing frame
    Matthijs F Wouda, Espen I Bengtson, Ellen Høyer, Alhed P Wesche, Vivien Jørgensen
    Journal of Rehabilitation and Assistive Technologies Engineering.2024;[Epub]     CrossRef
  • Aktuelle Aspekte der intensivmedizinischen Versorgung bei Schädel-Hirn-Trauma – Teil 2
    André Hagedorn, Helge Haberl, Michael Adamzik, Alexander Wolf, Matthias Unterberg
    AINS - Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie.2024; 59(07/08): 466.     CrossRef

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