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Korean J Crit Care Med > Volume 24(3); 2009 > Article
Korean Journal of Critical Care Medicine 2009;24(3): 176-180. doi: https://doi.org/10.4266/kjccm.2009.24.3.176
중환자실에서 Tigecycline과 Amikacin의 병합 치료 후 호전된 광범위약제내성 Acinetobacter baumannii 폐렴 1예-증례 보고-
임소연*ㆍ박소영*ㆍ전경만*ㆍ서지영*ㆍ김수현†ㆍ백경란‡ㆍ정두련‡
*성균관대학교 의과대학 삼성서울병원 내과학교실 호흡기내과, †서울의료원, ‡성균관대학교 의과대학 삼성서울병원 내과학교실 감염내과
Extreme Drug Resistant Acinetobacter Nosocomial Ventilator-Associated Pneumonia Treated Successfully with Tigecycline and Amikacin in Intensive Care Unit: A Case Report
So Yeon Lim, So Young Park, Kyeongman Jeon, Gee Young Suh, Suhyun Kim, Kyong Ran Peck, Doo Ryeon Chung
1Division of Pulmonary and Critical Care Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
2Seoul Medical Center, Seoul, Korea.
3Division of Infectious Diseases, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. drchung@skku.edu
ABSTRACT
Infections due to multidrug resistant Acinetobacter baumannii have become a challenging problem in intensive care units. Tigecycline is a derivative of minocyline, and has provided new hope for the treatment of multidrug-resistant A. baumannii infections. Because isolates showing reduced susceptibility to minocycline or tigecycline have emerged in many countries, empirical combination therapy has become common practice to treat patients infected with extreme drug-resistant A. baumannii. Herein we report a case of extreme drug-resistant A. baumannii infection successfully treated with tigecycline and amikacin.
Key Words: acinetobacter; amikacin; tigecycline; ventilator-associated pneumonia
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