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Korean J Crit Care Med > Volume 26(2); 2011 > Article
Korean Journal of Critical Care Medicine 2011;26(2): 114-116. doi: https://doi.org/10.4266/kjccm.2011.26.2.114
기계환기 치료 없이 회복한 신종플루에 의한 급성호흡곤란 증후군 -증례 보고-
중앙대학교 의과대학 내과학교실
H1N1 Influenza/A Associated ARDS Recovered without Mechanical Ventilatory Support: A Case Report
Byung Ook Lee, Jae Hee Lee, Sung Woon Park, Bo Min Kim, Jae Chol Choi, Jong Wook Shin, In Won Park, Byoung Whui Choi, Jae Yeol Kim
Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea. jykimmd@cau.ac.kr
An eighteen year-old female visited the ER in our hospital with fever of 38.5degrees C for 2 days. She also had cough, myalgia, and dyspnea. Chest PA and lung HRCT showed mild pulmonary edema at both hilar areas. However, she had severe hypoxia (PaO2; 58 mmHg in room air). RT-PCR for H1N1 influenza/A of pharyngeal swab was positive. Tamiflu (150 mg/d) with broad-spectrum antibiotics was prescribed. Two days later, her dyspnea aggravated and chest PA showed diffuse bilateral infiltration. PaO2 dropped to 70 mmHg (O2 10 L/min by face mask with reservoir bag). She was transferred to the MICU and the Tamiflu dose was doubled (300 mg/day). Mechanical ventilator was set aside to prepare respiratory failure. Fortunately, her symptoms and oxygenation improved and she was discharged with full recovery. Although, most cases of ARDS require mechanical ventilatory support, early and adequate dose of Tamiflu may avoid it in the case of ARDS developed by H1N1 influenza/A.
Key Words: ARDS; H1N1; pneumonia
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