1Department of Anesthesiology and Pain Medicine, Inje University College of Medicine, Busan, Korea
2Department of Anesthesiology and Pain Medicine, Inje University Seoul Paik Hospital, Seoul, Korea
3Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Seongnam, Korea
4Department of Anesthesiology and Pain Medicine, Seoul National University College of Medicine, Seoul, Korea
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Onset | Offset | Respiratory suppression | Cardiac suppression | Injection pain | Reverse | Severe adverse effect | |
---|---|---|---|---|---|---|---|
Propofol | Very rapid | Rapid | ++ to +++ | ++ to +++ | ++ | None | Septicemia due to contamination of formula, and propofol infusion syndrome |
Midazolam | Rapid | Slow and delayed with accumulation | + to ++ | + to ++ | 0 | Flumazenil | - |
Remimazolam | Very rapid | Rapid | + to ++ | 0 | 0 | Flumazenil | - |
Dexmedetomidine | >10 min | Slow | 0 to + | + to ++ | 0 | None | - |
Sevoflurane (inhalational anesthetics) | Very rapid | Rapid | + to ++ | ++ | - | None | Malignant hyperthermia |