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Right-sided infective endocarditis of a native valve with multiple embolus lesions
Miyeon Kimorcid, Ki Yung Booorcid, Jeong Rae Yooorcid
Acute and Critical Care 2023;38(4):513-514.
Published online: November 24, 2023

Department of Internal Medicine, Jeju National University College of Medicine, Jeju, Korea

Corresponding author: Jeong Rae Yoo Division of Infectious Disease, Department of Internal Medicine, Jeju National University College of Medicine, 102 Jejudaehang-ro, Jeju 54987, Korea Tel: +82-64-717-2286, Fax: +82-64-717-2286 Email:
• Received: September 22, 2023   • Revised: October 24, 2023   • Accepted: October 26, 2023

Copyright © 2023 The Korean Society of Critical Care Medicine

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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A 47-year-old man was transferred to our hospital with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia. On admission, the patient had multiple 1–3-cm-sized black dotlike erythematous lesions throughout the body (Figure 1A). In addition, he had multiple patchy consolidations in both lung fields (Figure 1B) and multifocal dots scattered in both fronto-parieto-temporal lobes (Figure 1C). On the 2nd day of admission, transthoracic echocardiography revealed a 2.25×1.5-cm-sized friable mass in the tricuspid septal leaflet (Figure 1D, Supplementary Videos 1 and 2). MRSA was isolated from the patient’s blood and skin lesions. Unexpectedly, no intracardiac shunt was shown on transthoracic and transesophageal echocardiography. Tricuspid septal leaflet repair and mass debridement had been performed in the referring hospital. MRSA was isolated from the debrided mass from the tricuspid valve.
In this case, atypical features were noted. Infective endocarditis occurred on a normal tricuspid valve, and a large vegetation was present, caused by MRSA. He also exhibited clinical signs of systemic embolization, despite the absence of congenital heart disease, central venous catheter use, and drug use, making this case particularly unique and challenging to diagnose and treat [1,2].


No potential conflict of interest relevant to this article was reported.




Conceptualization: JRY. Data curation: JRY, KYB. Formal analysis: JRY. Methodology: JRY, MK. Project administration: JRY. Visualization: JRY. Writing–original draft: MK. Writing–review & editing: JRY.

This study was approved by the Institutional Review Board at Jeju National University Hospital (No. 2023-07-006). The patient provided informed consent for publication of the report.
Supplementary materials can be found via

Supplementary Video 1.

Transthoracic echocardiogram, apical four-chamber view. A 47-year-old man without prior cardiac abnormalities was admitted with multiple septic embolic lesions and methicillin-resistant Staphylococcus aureus bacteremia. A transthoracic echocardiogram demonstrated a tricuspid septal leaflet with a 2.25×1.5-cm-sized friable vegetative lesion.

Supplementary Video 2.

Transthoracic echocardiogram, paralong axis view.
Figure 1.
(A) Multiple dot-like black erythematous lesions measuring 1–3 cm throughout the body. (B) Chest computed tomography revealing multiple nodules in both lungs. (C) Diffusion-weighted brain magnetic resonance imaging of lesions with high signal intensity, appearing as multiple scattered dots, in both fronto-parieto-temporal lobes. (D) Apical view of the four chambers on transthoracic echocardiography showing vegetation in the tricuspid valve indicated by yellow arrowheads.
  • 1. Shmueli H, Thomas F, Flint N, Setia G, Janjic A, Siegel RJ. Right-sided infective endocarditis 2020: challenges and updates in diagnosis and treatment. J Am Heart Assoc 2020;9:e017293. ArticlePubMedPMC
  • 2. Habib G, Lancellotti P, Antunes MJ, Bongiorni MG, Casalta JP, Del Zotti F, et al, ESC Scientific Document Group. 2015 ESC Guidelines for the management of infective endocarditis: The Task Force for the Management of Infective Endocarditis of the European Society of Cardiology (ESC). Endorsed by: European Association for Cardio-Thoracic Surgery (EACTS), the European Association of Nuclear Medicine (EANM). Eur Heart J 2015;36:3075-128.ArticlePubMed

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        Right-sided infective endocarditis of a native valve with multiple embolus lesions
        Acute Crit Care. 2023;38(4):513-514.   Published online November 24, 2023
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