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HOME > Acute Crit Care > Volume 27(4); 2012 > Article
Case Report Successful Brain Dead Donor Management with CRRT: A Case Report
Sang Hyun Lim, Young Joo Lee, Han Bum Joe, Jae Moung Lee, In Kyung Lee

DOI: https://doi.org/10.4266/kjccm.2012.27.4.286
1Department of Thoracic and Cardiovascular Surgery, Ajou University School of Medicine, Suwon, Korea.
2Department of Anesthesiology, Ajou University School of Medicine, Suwon, Korea. sicuab@hotmail.com
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Brain death results in adverse pathophysiologic effects in many brain-dead donors with cardiovascular instability. We experienced a brain-dead donor with continuous renal replacement therapy (CRRT) who was in a severe metabolic, electrolyte derangement and poor pulmonary function. The thirty-nine-year-old male patient with subarachnoid hemorrhage and intraventricular hemorrhage was admitted into the intensive care unit (ICU). After sudden cardiac arrest, he went into a coma state and was referred to as a potential organ donor. When he was transferred, his vital sign was unstable even under the high dose of inotropics and vasopressors. Even with aggressive treatment, the level of blood sugar was 454 mg/dl, serum K+ 7.1 mEq/L, lactate 5.33 mmol/L and PaO2/FiO2 60.3. We decided to start CRRT with the mode of continuous venovenous hemodiafiltration (CVVHDF). After 12 hours of CRRT, vital sign was maintained well without vasopressors, and blood sugar, serum potassium and lactate levels returned to 195 of PaO2/FiO2. Therefore, he was able to donate his two kidneys and his liver.


ACC : Acute and Critical Care