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Korean J Crit Care Med > Volume 24(1); 2009 > Article
Korean Journal of Critical Care Medicine 2009;24(1): 28-32. doi: https://doi.org/10.4266/kjccm.2009.24.1.28
3차 대학병원 내과계 중환자실 내 중증 패혈증의 유병률과 예후인자
울산대학교 의과대학 서울아산병원 외과학교실, *호흡기내과학교실
The Characteristics and Prognostic Factors of Severe Sepsis in Patients Who Were Admitted to a Medical Intensive Care Unit of a Tertiary Hospital
Suk Kyung Hong, Sang Bum Hong, Chae Man Lim, Younsuck Koh
1Department of Surgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
2Department of Pulmonary and Critical Care Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. yskoh@amc.seoul.kr
BACKGROUND: Severe sepsis is a major cause of morbidity and mortality in intensive care units. This study aimed to evaluate the prevalence, characteristics, outcomes and prognostic factors of severe sepsis in a medical intensive care unit (MICU) of a tertiary care hospital in Korea. METHODS: We retrospectively reviewed the medical chart of 249 patients who were admitted to a medical intensive care unit with severe sepsis. RESULTS: From January 2000 to December 2001, 3410 patients were admitted to the ICU. The prevalence of severe sepsis was 7.3%. The mortality of severe sepsis was 64.6%. The prognostic factors for severe sepsis were the number of organ systems that acutely failed (p = 0.036) and an admission route from general wards (p = 0.018). There was no difference in the outcome of severe sepsis according to infectious organisms (p = 0.24) and the site of infections (p = 0.38). CONCLUSIONS: Severe sepsis in the MICU is a common, expensive and often fatal condition. We expect that early rescucitation and recovery from acute organ system failure will improve the outcome of severe sepsis.
Key Words: infection; organ failure; severe sepsis
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