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- CPR/Resuscitation
- Plasma biomarkers for brain injury in extracorporeal membrane oxygenation
- Shrey Kapoor, Anna Kolchinski, Aaron M. Gusdon, Lavienraj Premraj, Sung-Min Cho
- Acute Crit Care. 2023;38(4):389-398. Published online November 29, 2023
- DOI: https://doi.org/10.4266/acc.2023.01368
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- 2 Web of Science
- 2 Crossref
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Abstract
PDF - Extracorporeal membrane oxygenation (ECMO) is a life-saving intervention for patients with refractory cardiorespiratory failure. Despite its benefits, ECMO carries a significant risk of neurological complications, including acute brain injury (ABI). Although standardized neuromonitoring and neurological care have been shown to improve early detection of ABI, the inability to perform neuroimaging in a timely manner is a major limitation in the accurate diagnosis of neurological complications. Therefore, blood-based biomarkers capable of detecting ongoing brain injury at the bedside are of great clinical significance. This review aims to provide a concise review of the current literature on plasma biomarkers for ABI in patients on ECMO support.
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Citations
Citations to this article as recorded by
- Pharmacological Inhibition of the HSPB1-NF-κB Axis Alleviates Brain Injury in a Rat Veno-Venous Extracorporeal Membrane Oxygenation Model
Xin Ma, Junzhe Du, Xueyang Shen, Jian Li, Xiaoqian Zhang, Qiming Zhao, Yongnan Li, Xiangyang Wu
Molecular Neurobiology.2026;[Epub] CrossRef - Predictive Markers of Neurological Complications in Patients Treated With Extracorporeal Membrane Oxygenation
Adeel Abbasi, Linn Ayers, Ron Balczon, Amy R. Nelson, Allison J. Bauman, Maya Cohen, Neelia Abadi, John R. Priest, Saraschandra Vallabhajosyula, Grayson L. Baird, Troy Stevens, Corey E. Ventetuolo
CHEST Critical Care.2025; 3(3): 100170. CrossRef
- Pharmacological Inhibition of the HSPB1-NF-κB Axis Alleviates Brain Injury in a Rat Veno-Venous Extracorporeal Membrane Oxygenation Model
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