Acute and Critical Care

Review Article

November 10, 2022

Target temperature management in traumatic brain injury with a focus on adverse events, recognition, and prevention

Kwang Wook Jo

Acute Crit Care. 2022;37(4):483-490.

• Targeted temperature management is one of the most promising neuroprotective methods to prevent secondary brain injury in patients with traumatic brain injury.
• Although many studies have not proven its effectiveness clearly so far, and there have been many problems due to side effects, its complications and side effects have been significantly reduced as general supportive technology develops.
• It is expected that clinical studies including patients with the proper indications and well-organized protocols for targeted temperature management can be conducted.

Review Article

November 30, 2022

Asynchronies during invasive mechanical ventilation: narrative review and update

Santiago Nicolás Saavedra, Patrick Valentino Sepúlveda Barisich, José Benito Parra Maldonado, Romina Belén Lumini, Alberto Gómez-González, Adrián Gallardo

Acute Crit Care. 2022;37(4):491-501.

- Asynchronies during mechanical ventilation have shown association with worse outcomes. - Early detection and treatment could improve patient survival.
- There are different classifications of asynchrony.
- A distinction based on phase variables helps to better understand its causes and early detection.
- Complementary methods, such as ultrasonography, esophageal pressure or visual inspection, collaborate and reinforce the detection, diagnosis and treatment of these entities.

Review Article

November 21, 2022

Lung ultrasound for evaluation of dyspnea: a pictorial review

Aparna Murali, Anjali Prakash, Rashmi Dixit, Monica Juneja, Naresh Kumar

Acute Crit Care. 2022;37(4):502-515.

• Lung Ultrasound is a useful tool, especially for bedside diagnosis of dyspnea in the acute and critical care setting.
• Lung Ultrasound is based on analyzing the ultrasound artifacts generated, and applying the principles of the BLUE (Bedside Lung Ultrasound Examination) protocol to arrive at a diagnosis.
• Correlation with history and clinical findings at the bedside further adds to the diagnostic value of this quick and feasible technique

Review Article

October 18, 2022

Barriers and facilitators in the provision of palliative care in adult intensive care units: a scoping review

Christantie Effendy, Yodang Yodang, Sarah Amalia, Erna Rochmawati

Acute Crit Care. 2022;37(4):516-526.

- The provision of palliative care in intensive care units (ICUs) is advocated to improve end-of-life care and patient’ quality of life, and to reduce hospital admission and hospital stays.
- This review maps a lack of capabilities and family boundaries as barriers in the integration of palliative care in the ICU
- Experiences and supportive behaviors are identified as facilitators in the provision of palliative care in ICUs.

Original Article

August 19, 2022

Validation of presepsin measurement for mortality prediction of sepsis: a preliminary study

Seung Min Baik, Jin Park, Tae Yoon Kim, Se Hong Choi, Kyung Sook Hong

Acute Crit Care. 2022;37(4):527-532.

 Sepsis and septic shock are the leading causes of death in critically ill patients.
 Procalcitonin, presepsin, and lactate are some of the biomarkers available for diagnosis of sepsis and prediction of sepsis-induced mortality.
 Serum presepsin levels may serve as an effective biomarker for prediction of sepsis-induced mortality.

Original Article

October 6, 2022

The prognostic impact of rheumatoid arthritis in sepsis: a population-based analysis

Lavi Oud, John Garza

Acute Crit Care. 2022;37(4):533-542.

• Patients with rheumatoid arthritis had lower risk of short-term mortality than those without rheumatoid arthritis among septic patients.
• This finding suggests that the increased risk of infection-related mortality in patients with rheumatoid arthritis compared to the general population is due to their increased risk of sepsis, rather than higher case fatality among septic patients.

Original Article

October 21, 2022

Incidence and risk factors associated with progression to severe pneumonia among adults with non-severe Legionella pneumonia

Jin-Young Huh, Sang-Ho Choi, Kyung-Wook Jo, Jin Won Huh, Sang-Bum Hong, Tae Sun Shim, Chae-Man Lim, Younsuck Koh

Acute Crit Care. 2022;37(4):543-549.

 Among 155 patients with Legionella pneumonia at presentation, 58 patients (37.4%) had severe pneumonia and 97 patients (62.6%) had non-severe pneumonia; 28 of the 97 patients (28.9%) progressed to severe pneumonia.
 Platelet count ≤150,000/mm3 and delayed antibiotic treatment >1 day were factors associated with progression to severe pneumonia in initially non-severe Legionella pneumonia patients.

Original Article

October 6, 2022

The frequency and seasonal distribution of viral infection in patients with community-acquired pneumonia and its impact on the prognosis

Kyung Jun Kim, Doh Hyung Kim

Acute Crit Care. 2022;37(4):550-560.

⦁ The most frequently detected viruses were influenza A virus (44%), followed by rhinovirus (19%), influenza B (13%), and adenovirus (6%) in community-acquired pneumonia (CAP) patients.
⦁ Viral-bacterial coinfection was significantly more frequent in elderly patients over 65 than both viral alone and bacterial alone infection.
⦁ Compared with viral alone infection, viral-bacterial coinfection was the stronger predictor of 30-day mortality in CAP than bacterial alone infection.

Original Article

October 28, 2022

Association between timing of intubation and mortality in patients with idiopathic pulmonary fibrosis

Eunhye Bae, Jimyung Park, Sun Mi Choi, Jinwoo Lee, Sang-Min Lee, Hong Yeul Lee

Acute Crit Care. 2022;37(4):561-570.

• Delayed intubation is associated with poor prognosis in patients with respiratory failure.
• However, the effect of delayed intubation in patients with idiopathic pulmonary fibrosis (IPF) remains unknown.
• Delayed intubation, defined as use of high-concentration oxygen therapy for at least 48 hours before tracheal intubation, was significantly associated with increased risk of intensive care unit mortality compared to early intubation in patients with IPF that required mechanical ventilation.
• As with other causes of respiratory failure, tracheal intubation should not be delayed if needed in IPF patients who have failed high-concentration oxygen therapy, especially when lung transplantation is being considered.

Original Article

November 10, 2022

Extravascular lung water index, pulmonary vascular permeability index, and global end-diastolic volume index in mechanically ventilated COVID-19 patients requiring prone position ventilation: a preliminary retrospective study

Rosanna Carmela De Rosa, Antonio Romanelli, Michele Gallifuoco, Giovanni Messina, Marianne Di Costanzo, Antonio Corcione

Acute Crit Care. 2022;37(4):571-579.

- Data provided by transpulmonary thermodilution monitoring can be helpful for the clinical management of patients with coronavirus disease 2019 (COVID-19)-associated acute respiratory distress syndrome requiring prone position ventilation.
- During prone position ventilation, extravascular lung water index (EVLWi) values decrease, while pulmonary vascular permeability index and global end-diastolic volume index variations were not statistically significant.
- EVLWi values showed a statistically significant relationship with PaO2/FiO2 values in the supine position.
- EVLWi evaluation can help clinicians determine whether deterioration of gas exchange is related to fluid overload or worsening disease.

Original Article

September 8, 2022

An algorithm to predict the need for invasive mechanical ventilation in hospitalized COVID-19 patients: the experience in Sao Paulo

Eduardo Atsushi Osawa, Alexandre Toledo Maciel

Acute Crit Care. 2022;37(4):580-591.

⦁ In our cohort hospitalized for coronavirus disease 2019 (COVID-19), we observed a good accuracy for mechanical ventilation prediction with some laboratory tests assessed at hospital admission including C-reactive protein and lactate dehydrogenase.
⦁ Our algorithm identified in the multivariate analysis eight variables as significant predictors for mechanical ventilation: male sex, age, obesity, duration from symptom onset to hospital admission, oxygen saturation, C-reactive protein, neutrophil-to-lymphocyte ratio and lactate dehydrogenase all assessed at admission.
⦁ Despite the existence of many predictive models in COVID-19, our algorithm adds novelty to the literature by including a simple but often neglected variable: duration from symptom onset to hospital admission.

Original Article

October 27, 2022

Agreement between two methods for assessment of maximal inspiratory pressure in patients weaning from mechanical ventilation

Emanuelle Olympia Silva Ribeiro, Rik Gosselink, Lizandra Eveline da Silva Moura, Raissa Farias Correia, Wagner Souza Leite, Maria das Graças Rodrigues de Araújo, Armele Dornelas de Andrade, Daniella Cunha Brandão, Shirley Lima Campos

Acute Crit Care. 2022;37(4):592-600.

⦁ Maximal inspiratory pressures (MIPs) derived from one-way valve inspiratory occlusion and a digital manometer and those from repetitively tapered flow resistive inspirations and an electronic loading device are discordant.
⦁ MIP assessment using repetitively tapered flow resistive inspirations and an electronic loading device is not reliable in uncooperative patients being weaned from mechanical ventilation.

Original Article

August 18, 2022

Association between C-reactive protein-to-albumin ratio and 6-month mortality in out-of-hospital cardiac arrest

Hui Hwan Kim, Ji Ho Lee, Dong Hun Lee, Byung Kook Lee

Acute Crit Care. 2022;37(4):601-609.

▪ C-reactive protein-to-albumin ratio (CAR) is an effective marker of a systemic inflammatory response, including post-cardiac arrest syndrome (PCAS).
▪ Targeted temperature management can affect the systemic inflammatory response in the body by lowering the temperature.
▪ CAR more than 48 hours after cardiac arrest was an independent predictor for 6-month mortality in patients with PCAS.

Original Article

October 27, 2022

Gun Woo Kim, Young-Il Roh, Kyoung-Chul Cha, Sung Oh Hwang, Jae Hun Han, Woo Jin Jung

Acute Crit Care. 2022;37(4):610-617.

Supporting proper nutrition can reduce a patient's hospital stay and reduce patient morbidity.
Early nutritional support for resuscitated patients demonstrated no significant difference in clinical complications when compared to delayed nutritional support.

Original Article

October 18, 2022

Comparison of mNUTRIC-S2 and mNUTRIC scores to assess nutritional risk and predict intensive care unit mortality

So Jeong Kim, Hong Yeul Lee, Sun Mi Choi, Sang-Min Lee, Jinwoo Lee

Acute Crit Care. 2022;37(4):618-626.

• The modified Nutrition Risk in the Critically Ill (mNUTRIC)-S2 score, which uses the Simplified Acute Physiology Score (SAPS) II instead of the Acute Physiology and Chronic Health Evaluation (APACHE) II, was significantly associated with intensive care unit (ICU) mortality.
• The suggested cutoff score of 5 was appropriate to screen Korean critically ill patients.
• Patients with mNUTRIC-S2 score ≥5 had a higher risk of ICU mortality, which was not observed with mNUTRIC score.

Original Article

October 19, 2022

Incidence and associated factors of pediatric post-intensive care syndrome using the VSCAREMD model

Paweethida Tippayawong, Chanapai Chaiyakulsil

Acute Crit Care. 2022;37(4):627-635.

- Physical, cognitive, mental, and social morbidity were found in 64.2%, 26.3%, 13.7%, and 38.9% of the children, respectively.
- Prolonged intensive care stay greater than 7 days was associated with post-intensive care syndrome.
- The incidence of post-intensive care syndrome in children using the VSCAREMD model was high and associated with prolonged intensive care stays.

Original Article

October 19, 2022

Perioperative hemodynamic protective assessment of adaptive support ventilation usage in pediatric surgical patients

Dmytro Dmytriiev, Mykola Melnychenko, Oleksandr Dobrovanov, Oleksandr Nazarchuk, Marian Vidiscak

Acute Crit Care. 2022;37(4):636-643.

• Most patients require mechanical ventilation during surgery, and there is currently no clear evidence of the benefits of any ventilation mode.
• Low tidal volumes and low positive end-expiratory pressure should be used when adjusting the ventilation mode.
• The aim of our study was to evaluate the hemodynamic protective effects of pressure-controlled ventilation (PCV) and adaptive support ventilation (ASV) mode perioperative ventilation based on indicators of non-invasive hemodynamic monitoring.
• In our study, ASV mode perioperative ventilation was more protective than PCV mode.
• Hemodynamically-controlled mechanical ventilation reduces the negative impact of cardiopulmonary interactions.

Original Article

November 11, 2022

Characteristics and timing of mortality in children dying in pediatric intensive care: a 5-year experience

Edin Botan, Emrah Gün, Emine Kübra Şden, Cansu Yöndem, Anar Gurbanov, Burak Balaban, Fevzi Kahveci, Hasan Özen, Hacer Uçmak, Ali Genco Gençay, et al.

Acute Crit Care. 2022;37(4):644-653.

-Invasive infections, chronic diseases, and the spectrum of septic shock are important causes of mortality in pediatric intensive care unit.
-Understanding early death trends and characteristics of children who die early is crucial to obtaining a rapid and targeted clinical trial record before death.
-We found that rates of neurological findings, hypotension, oliguria, acidosis, coagulation disorder, and cardiac arrest and Pediatric Risk of Mortality III scores were higher in children who died early compared to those who died later.

Original Article

October 26, 2022

Multicenter validation of a deep-learning-based pediatric early-warning system for prediction of deterioration events

Yunseob Shin, Kyung-Jae Cho, Yeha Lee, Yu Hyeon Choi, Jae Hwa Jung, Soo Yeon Kim, Yeo Hyang Kim, Young A Kim, Joongbum Cho, Seong Jong Park, et al.

Acute Crit Care. 2022;37(4):654-666.

 We developed a deep-learning-based pediatric early-warning system (pDEWS) and performed a multicenter validation.
 pDEWS showed excellent performance in predicting clinical deterioration events regardless of clinical setting.

Current Issue: Volume 37(4); Nov 2022

Target temperature management in traumatic brain injury with a focus on adverse events, recognition, and prevention Kwang Wook Jo Acute Crit Care. 2022;37(4):483-490. Review Article November 10, 2022 Full text PubReader ePub PDF	Asynchronies during invasive mechanical ventilation: narrative review and update Santiago Nicolás Saavedra, Patrick Valentino Sepúlveda Barisich, José Benito Parra Maldonado, Romina Belén Lumini, Alberto Gómez-González, Adrián Gallardo Acute Crit Care. 2022;37(4):491-501. Review Article November 30, 2022 Full text PubReader ePub PDF Supplementary Material
Lung ultrasound for evaluation of dyspnea: a pictorial review Aparna Murali, Anjali Prakash, Rashmi Dixit, Monica Juneja, Naresh Kumar Acute Crit Care. 2022;37(4):502-515. Review Article November 21, 2022 Full text PubReader ePub PDF Supplementary Material	Barriers and facilitators in the provision of palliative care in adult intensive care units: a scoping review Christantie Effendy, Yodang Yodang, Sarah Amalia, Erna Rochmawati Acute Crit Care. 2022;37(4):516-526. Review Article October 18, 2022 Full text PubReader ePub PDF
Validation of presepsin measurement for mortality prediction of sepsis: a preliminary study Seung Min Baik, Jin Park, Tae Yoon Kim, Se Hong Choi, Kyung Sook Hong Acute Crit Care. 2022;37(4):527-532. Original Article August 19, 2022 Full text PubReader ePub PDF	The prognostic impact of rheumatoid arthritis in sepsis: a population-based analysis Lavi Oud, John Garza Acute Crit Care. 2022;37(4):533-542. Original Article October 6, 2022 Full text PubReader ePub PDF Supplementary Material
Incidence and risk factors associated with progression to severe pneumonia among adults with non-severe Legionella pneumonia Jin-Young Huh, Sang-Ho Choi, Kyung-Wook Jo, Jin Won Huh, Sang-Bum Hong, Tae Sun Shim, Chae-Man Lim, Younsuck Koh Acute Crit Care. 2022;37(4):543-549. Original Article October 21, 2022 Full text PubReader ePub PDF	The frequency and seasonal distribution of viral infection in patients with community-acquired pneumonia and its impact on the prognosis Kyung Jun Kim, Doh Hyung Kim Acute Crit Care. 2022;37(4):550-560. Original Article October 6, 2022 Full text PubReader ePub PDF
Association between timing of intubation and mortality in patients with idiopathic pulmonary fibrosis Eunhye Bae, Jimyung Park, Sun Mi Choi, Jinwoo Lee, Sang-Min Lee, Hong Yeul Lee Acute Crit Care. 2022;37(4):561-570. Original Article October 28, 2022 Full text PubReader ePub PDF	Extravascular lung water index, pulmonary vascular permeability index, and global end-diastolic volume index in mechanically ventilated COVID-19 patients requiring prone position ventilation: a preliminary retrospective study Rosanna Carmela De Rosa, Antonio Romanelli, Michele Gallifuoco, Giovanni Messina, Marianne Di Costanzo, Antonio Corcione Acute Crit Care. 2022;37(4):571-579. Original Article November 10, 2022 Full text PubReader ePub PDF
An algorithm to predict the need for invasive mechanical ventilation in hospitalized COVID-19 patients: the experience in Sao Paulo Eduardo Atsushi Osawa, Alexandre Toledo Maciel Acute Crit Care. 2022;37(4):580-591. Original Article September 8, 2022 Full text PubReader ePub PDF	Agreement between two methods for assessment of maximal inspiratory pressure in patients weaning from mechanical ventilation Emanuelle Olympia Silva Ribeiro, Rik Gosselink, Lizandra Eveline da Silva Moura, Raissa Farias Correia, Wagner Souza Leite, Maria das Graças Rodrigues de Araújo, Armele Dornelas de Andrade, Daniella Cunha Brandão, Shirley Lima Campos Acute Crit Care. 2022;37(4):592-600. Original Article October 27, 2022 Full text PubReader ePub PDF
Association between C-reactive protein-to-albumin ratio and 6-month mortality in out-of-hospital cardiac arrest Hui Hwan Kim, Ji Ho Lee, Dong Hun Lee, Byung Kook Lee Acute Crit Care. 2022;37(4):601-609. Original Article August 18, 2022 Full text PubReader ePub PDF Supplementary Material	Diet-related complications according to the timing of enteral nutrition support in patients who recovered from out-of-hospital cardiac arrest: a propensity score matched analysis Gun Woo Kim, Young-Il Roh, Kyoung-Chul Cha, Sung Oh Hwang, Jae Hun Han, Woo Jin Jung Acute Crit Care. 2022;37(4):610-617. Original Article October 27, 2022 Full text PubReader ePub PDF Supplementary Material
Comparison of mNUTRIC-S2 and mNUTRIC scores to assess nutritional risk and predict intensive care unit mortality So Jeong Kim, Hong Yeul Lee, Sun Mi Choi, Sang-Min Lee, Jinwoo Lee Acute Crit Care. 2022;37(4):618-626. Original Article October 18, 2022 Full text PubReader ePub PDF	Incidence and associated factors of pediatric post-intensive care syndrome using the VSCAREMD model Paweethida Tippayawong, Chanapai Chaiyakulsil Acute Crit Care. 2022;37(4):627-635. Original Article October 19, 2022 Full text PubReader ePub PDF
Perioperative hemodynamic protective assessment of adaptive support ventilation usage in pediatric surgical patients Dmytro Dmytriiev, Mykola Melnychenko, Oleksandr Dobrovanov, Oleksandr Nazarchuk, Marian Vidiscak Acute Crit Care. 2022;37(4):636-643. Original Article October 19, 2022 Full text PubReader ePub PDF	Characteristics and timing of mortality in children dying in pediatric intensive care: a 5-year experience Edin Botan, Emrah Gün, Emine Kübra Şden, Cansu Yöndem, Anar Gurbanov, Burak Balaban, Fevzi Kahveci, Hasan Özen, Hacer Uçmak, Ali Genco Gençay, et al. Acute Crit Care. 2022;37(4):644-653. Original Article November 11, 2022 Full text PubReader ePub PDF
Multicenter validation of a deep-learning-based pediatric early-warning system for prediction of deterioration events Yunseob Shin, Kyung-Jae Cho, Yeha Lee, Yu Hyeon Choi, Jae Hwa Jung, Soo Yeon Kim, Yeo Hyang Kim, Young A Kim, Joongbum Cho, Seong Jong Park, et al. Acute Crit Care. 2022;37(4):654-666. Original Article October 26, 2022 Cited By 1 Full text PubReader ePub PDF Supplementary Material	An advanced pediatric early warning system: a reliable sentinel, not annoying extra work Young Joo Han Acute Crit Care. 2022;37(4):667-668. Editorial November 29, 2022 Full text PubReader ePub PDF
Continuous renal replacement therapy increased plasma cholinesterase activity in a case of acute organophosphate poisoning In Ho Kwon, Jinwoo Jeong, Yuri Choi Acute Crit Care. 2022;37(4):669-671. Case Report November 16, 2021 Full text PubReader ePub PDF	Real-time distinct visualization of barotrauma risk monitored by electrical impedance tomography in a COVID-19 and latent tuberculosis case Wagner Souza Leite, Shirley Lima Campos, Daniella Cunha Brandão, Caio César Araújo Morais, Armèle Dornelas de Andrade Acute Crit Care. 2022;37(4):672-673. Images in Critical Care September 21, 2022 Full text PubReader ePub PDF
Meta-analysis assessing the effectiveness of intravenous vitamin C in patients with sepsis and septic shock Muhammad Ali Tariq, Hamza Amin, Uzair Ali Acute Crit Care. 2022;37(4):674-677. Letter to the Editor October 21, 2022 Full text PubReader ePub PDF Supplementary Material	The incidence of acute acalculous cholecystitis in critically ill COVID-19 patients Diego Franch-Llasat, Raquel Sabaté-Ortigues, Naya Bellaubí-Pallarés, Fabián Andrés-Castrillo, Sònia Comí-Codina, Ferran Roche-Campo Acute Crit Care. 2022;37(4):678-680. Letter to the Editor September 21, 2022 Full text PubReader ePub PDF
Diaphragm ultrasound in weaning from mechanical ventilation: a last step to predict successful extubation? Domenica Di Costanzo, Mariano Mazza, Antonio Esquinas Acute Crit Care. 2022;37(4):681-682. Letter to the Editor May 31, 2022 Full text PubReader ePub PDF	Dangers in using beta-blockers in patients with venovenous extracorporeal membrane oxygenation Diego Rodríguez Álvarez, Elena Pérez-Costa, Juan José Menéndez Suso Acute Crit Care. 2022;37(4):683-684. Letter to the Editor July 18, 2022 Full text PubReader ePub PDF
Frequentist against Bayesian statistics: tug of war! Abhijit Nair Acute Crit Care. 2022;37(4):685-686. Letter to the Editor October 21, 2022 Full text PubReader ePub PDF	Current status of the rapid response system and early warning score: a survey-based analysis Sang-Hyeon Park, Jeehoon Kang, Tae Jung Kim, Hong Yeul Lee, Hyun-Jai Cho, Sang-Min Lee Acute Crit Care. 2022;37(4):687-689. Letter to the Editor November 21, 2022 Full text PubReader ePub PDF Supplementary Material
A comprehensive intensive care for senior citizens: the need for public health policy Dalmacito A. Cordero Jr Acute Crit Care. 2022;37(4):690-692. Letter to the Editor November 10, 2022 Full text PubReader ePub PDF	Contrast media mimicking subarachnoid hemorrhage after intrathecal injection in a patient with Creutzfeldt-Jakob disease Taegyun Kim Corrects: Acute Crit Care 2022;37(3):474 Acute Crit Care. 2022;37(4):693-693. Corrigendum November 30, 2022 Full text PubReader ePub PDF

The Korean Society of Critical Care Medicine

First decision

35 Days

Publication after acceptance

63 Days

Submission to publication

129 Days

Acceptance rate

35 %

*Last 12 months

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