Acute and Critical Care

Review Article

August 12, 2021

Identification and infection control of carbapenem-resistant Enterobacterales in intensive care units

Jongyoun Yi, Kye-Hyung Kim

Acute Crit Care. 2021;36(3):175-184.

▪ Due to limited treatment options, invasive carbapenemresistant Enterobacterales (CRE) colonization and infection in critically ill patients are associated with high mortality.
▪ The prevalence of CRE and carbapenemase-producing CRE continues to increase.
▪ Infection control measures, including hand hygiene, contact precaution, environmental control, and active surveillance should be implemented to reduce mortality due to CRE infection.

Review Article

June 30, 2021

The efficacy of vitamin C, thiamine, and corticosteroid therapy in adult sepsis patients: a systematic review and meta-analysis

Manoj Kumar Reddy Somagutta, Maria Kezia Lourdes Pormento, Muhammad Adnan Khan, Alaa Hamdan, Namrata Hange, Manish KC, Sukrut Pagad, Molly Sanjay Jain, Sivasthikka Lingarajah, Vishal Sharma, et al.

Acute Crit Care. 2021;36(3):185-200.

▪ Several studies have suggested favorable outcomes when using hydrocortisone, ascorbic acid (vitamin C), and thiamine (HAT) in patients with sepsis.
▪ A pooled analysis showed no significant benefit of HAT therapy on patient mortality or the length of hospital stay.
▪ A pooled analysis from the randomized controlled trials indicated that HAT therapy significantly reduced the duration of vasopressor use among sepsis patients and improved their Sequential Organ Failure Assessment scores.

Original Article

August 10, 2021

The Mount Sinai Hospital Institute for critical care medicine response to the COVID-19 pandemic

Jennifer Wang, Evan Leibner, Jaime B. Hyman, Sanam Ahmed, Joshua Hamburger, Jean Hsieh, Neha Dangayach, Pranai Tandon, Umesh Gidwani, Andrew Leibowitz, et al.

Acute Crit Care. 2021;36(3):201-207.

▪ This review provides a roadmap for hospitals and health systems on how to prepare for a surge in critical care capacity.
▪ The coronavirus disease 2019 pandemic requires a team effort across multiple disciplines to manage a surge of critically ill patients.

Original Article

August 12, 2021

Impact of prone position on outcomes of COVID-19 patients with spontaneous breathing

Mabrouk Bahloul, Sana Kharrat, Malek Hafdhi, Anis Maalla, Olfa Turki, Kamilia Chtara, Rania Ammar, Basma Suissi, Chokri Ben Hamida, Hedi Chelly, et al.

Acute Crit Care. 2021;36(3):208-214.

▪ Early application of prone position (PP) can improve severe hypoxemia and tachypnea in coronavirus disease 2019 (COVID-19) patients with spontaneous breathing.
▪ Early application of PP does not seem to be associated with a reduction in the use of invasive mechanical ventilation.
▪ Early application of PP does not seem to be associated with a reduction in mortality rate in COVID-19 patients with spontaneous breathing.
▪ Randomized controlled trials are needed to confirm the beneficial effects of PP in COVID-19 patients with spontaneous breathing.

Original Article

July 26, 2021

Sepsis-induced cardiomyopathy is associated with higher mortality rates in patients with sepsis

Balaram Krishna J Hanumanthu, Anika Sasidharan Nair, Adarsh Katamreddy, Jason S Gilbert, Jee Young You, Obiageli Lynda Offor, Ankit Kushwaha, Ankita Krishnan, Marzio Napolitano, Leonidas Palaidimos, et al.

Acute Crit Care. 2021;36(3):215-222.

▪ Sepsis-induced cardiomyopathy (SIC) is associated with a higher mortality rate in patients with sepsis, even following adjustment for sepsis severity scores in the final analysis of mortality.
▪ Factors indicating the severity of sepsis (such as low albumin level) rather than those indicating cardiac risk (e.g., diabetes mellitus, cardiac biomarkers) were associated with the development of SIC.
▪ Biventricular dysfunction was more common than isolated left ventricular dysfunction in SIC.

Original Article

July 30, 2021

Comparison of characteristics and ventilatory course between coronavirus disease 2019 and Middle East respiratory syndrome patients with acute respiratory distress syndrome

Imran Khalid, Romaysaa M Yamani, Maryam Imran, Muhammad Ali Akhtar, Manahil Imran, Rumaan Gul, Tabindeh Jabeen Khalid, Ghassan Y Wali

Acute Crit Care. 2021;36(3):223-231.

▪ In our comparison of coronavirus disease 2019 and Middle East respiratory syndrome patients with acute respiratory distress syndrome (ARDS), the former had higher initial C-reactive protein level, were more likely to receive a trial of high-flow oxygen, and experience delayed intubation.
▪ Postintubation, however, respiratory and ventilatory parameters (including tidal volume, fraction of inspired oxygen, and peak and plateau pressures) and their progression were similar between groups.
▪ ARDS mortality is extremely high in both groups, emphasizing the importance of early intervention.

Original Article

August 31, 2021

Intensive care unit professionals during the COVID-19 pandemic in Spain: social and work-related variables, COVID-19 symptoms, worries, and generalized anxiety levels

Fernando J. García-Hedrera, Fernanda Gil-Almagro, F. Javier Carmona-Monge, Cecilia Peñacoba-Puente, Patricia Catalá-Mesón, Lilian Velasco-Furlong

Acute Crit Care. 2021;36(3):232-241.

▪ Organizational issues and perceived risks seem to affect healthcare worker (HCW) mental health.
▪ Worry about self-infection was an important source of stress for HCW during the first wave of the pandemic.
▪ Regions in Spain differed widely in the availability of personal protective equipment and perceived workload from March to May 2020, which needs to be addressed to ensure that all regions have equal resources in future crisis situations.

Original Article

August 12, 2021

Perfusion parameters during cardiopulmonary bypass as a predictor of acute kidney injury after aortic valve replacement

Yeiwon Lee, Sue Hyun Kim, Ho Young Hwang, Suk Ho Sohn, Jae Woong Choi, Kyung Hwan Kim

Acute Crit Care. 2021;36(3):242-248.

▪ The actual lowest pump flow compared to the target pump flow based on oxygen delivery (DO2) might be a predictor of postoperative acute kidney injury after cardiac surgery.
▪ Female sex, stroke history, emergency operation, and transfusion of red blood cells were significant risk factors of postoperative acute kidney injury after cardiac surgery.

Original Article

July 26, 2021

Effects of high-flow nasal cannula in patients with mild to moderate hypercapnia: a prospective observational study

Kyung Hun Nam, Hyung Koo Kang, Sung-Soon Lee, So-Hee Park, Sung Wook Kang, Jea Jun Hwang, So Young Park, Won Young Kim, Hee Jung Suh, Eun Young Kim, et al.

Acute Crit Care. 2021;36(3):249-255.

▪ When high-flow nasal cannula was applied in moderate hypercapnia patients without severe respiratory acidosis, reduction of carbon dioxide and correction of pH was seen.
▪ Progression to mechanical ventilation was comparable to previous studies.
▪ We suggest that high-flow nasal cannula could be a safe alternative for oxygen delivery in hypercapnia patients who do not need immediate mechanical ventilation.

Original Article

July 26, 2021

Clinical features and outcomes of critically ill patients with Elizabethkingia meningoseptica: an emerging pathogen

Abdullah Umair, Nosheen Nasir

Acute Crit Care. 2021;36(3):256-261.

▪ Elizabethkingia meningoseptica is an opportunistic pathogen infecting people in the extremes of age and the immunocompromised, especially in intensive care settings.
▪ We are describing the largest case series to date reporting E. meningoseptica infections.
▪ Our study found that Chryseobacterium meningosepticum is an emerging nosocomial pathogen causing mortality in patients requiring intensive care and outcomes are better if isolates are susceptible to quinolones.

Current Issue: Volume 36(3); Aug 2021

Identification and infection control of carbapenem-resistant Enterobacterales in intensive care units Jongyoun Yi, Kye-Hyung Kim Acute Crit Care. 2021;36(3):175-184. Review Article August 12, 2021 Full text PubReader ePub PDF	The efficacy of vitamin C, thiamine, and corticosteroid therapy in adult sepsis patients: a systematic review and meta-analysis Manoj Kumar Reddy Somagutta, Maria Kezia Lourdes Pormento, Muhammad Adnan Khan, Alaa Hamdan, Namrata Hange, Manish KC, Sukrut Pagad, Molly Sanjay Jain, Sivasthikka Lingarajah, Vishal Sharma, et al. Acute Crit Care. 2021;36(3):185-200. Review Article June 30, 2021 Full text PubReader ePub PDF Supplementary Material
The Mount Sinai Hospital Institute for critical care medicine response to the COVID-19 pandemic Jennifer Wang, Evan Leibner, Jaime B. Hyman, Sanam Ahmed, Joshua Hamburger, Jean Hsieh, Neha Dangayach, Pranai Tandon, Umesh Gidwani, Andrew Leibowitz, et al. Acute Crit Care. 2021;36(3):201-207. Original Article August 10, 2021 Cited By 1 Full text PubReader ePub PDF Supplementary Material	Impact of prone position on outcomes of COVID-19 patients with spontaneous breathing Mabrouk Bahloul, Sana Kharrat, Malek Hafdhi, Anis Maalla, Olfa Turki, Kamilia Chtara, Rania Ammar, Basma Suissi, Chokri Ben Hamida, Hedi Chelly, et al. Acute Crit Care. 2021;36(3):208-214. Original Article August 12, 2021 Full text PubReader ePub PDF
Sepsis-induced cardiomyopathy is associated with higher mortality rates in patients with sepsis Balaram Krishna J Hanumanthu, Anika Sasidharan Nair, Adarsh Katamreddy, Jason S Gilbert, Jee Young You, Obiageli Lynda Offor, Ankit Kushwaha, Ankita Krishnan, Marzio Napolitano, Leonidas Palaidimos, et al. Acute Crit Care. 2021;36(3):215-222. Original Article July 26, 2021 Full text PubReader ePub PDF	Comparison of characteristics and ventilatory course between coronavirus disease 2019 and Middle East respiratory syndrome patients with acute respiratory distress syndrome Imran Khalid, Romaysaa M Yamani, Maryam Imran, Muhammad Ali Akhtar, Manahil Imran, Rumaan Gul, Tabindeh Jabeen Khalid, Ghassan Y Wali Acute Crit Care. 2021;36(3):223-231. Original Article July 30, 2021 Full text PubReader ePub PDF
Intensive care unit professionals during the COVID-19 pandemic in Spain: social and work-related variables, COVID-19 symptoms, worries, and generalized anxiety levels Fernando J. García-Hedrera, Fernanda Gil-Almagro, F. Javier Carmona-Monge, Cecilia Peñacoba-Puente, Patricia Catalá-Mesón, Lilian Velasco-Furlong Acute Crit Care. 2021;36(3):232-241. Original Article August 31, 2021 Full text PubReader ePub PDF	Perfusion parameters during cardiopulmonary bypass as a predictor of acute kidney injury after aortic valve replacement Yeiwon Lee, Sue Hyun Kim, Ho Young Hwang, Suk Ho Sohn, Jae Woong Choi, Kyung Hwan Kim Acute Crit Care. 2021;36(3):242-248. Original Article August 12, 2021 Full text PubReader ePub PDF
Effects of high-flow nasal cannula in patients with mild to moderate hypercapnia: a prospective observational study Kyung Hun Nam, Hyung Koo Kang, Sung-Soon Lee, So-Hee Park, Sung Wook Kang, Jea Jun Hwang, So Young Park, Won Young Kim, Hee Jung Suh, Eun Young Kim, et al. Acute Crit Care. 2021;36(3):249-255. Original Article July 26, 2021 Full text PubReader ePub PDF	Clinical features and outcomes of critically ill patients with Elizabethkingia meningoseptica: an emerging pathogen Abdullah Umair, Nosheen Nasir Acute Crit Care. 2021;36(3):256-261. Original Article July 26, 2021 Full text PubReader ePub PDF
Rapid communication for effective medical resource allocation in the COVID-19 pandemic Kwangha Lee Acute Crit Care. 2021;36(3):262-263. Editorial August 31, 2021 Full text PubReader ePub PDF	Circumferential esophageal perforation resulting in tension hydropneumothorax in a patient with septic shock Saad Saffo, James Farrell, Anil Nagar Acute Crit Care. 2021;36(3):264-268. Case Report March 11, 2021 Full text PubReader ePub PDF
Thoracomyoplasty and perioperative negative wound pressure therapy for bronchopleural fistula after trans-sternal bronchial closure Jinwook Hwang, Jeong In Hong, Hong Ju Shin, Jae Seung Shin, Je Hyeong Kim Acute Crit Care. 2021;36(3):269-273. Image in Critical Care August 3, 2021 Full text PubReader ePub PDF

The Korean Society of Critical Care Medicine

First decision

27 Days

Publication after acceptance

57 Days

Submission to publication

126 Days

Acceptance rate

25 %

*Last 12 months

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