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Review
Status Epilepticus and Beyond: A Clinical Review of Status Epilepticus and an Update on Current Management Strategies in Super-refractory Status Epilepticus
Roy Poblete, Gene Sung
Korean J Crit Care Med. 2017;32(2):89-105.   Published online May 31, 2017
DOI: https://doi.org/10.4266/kjccm.2017.00252
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  • 4 Web of Science
  • 6 Crossref
AbstractAbstract PDF
Status epilepticus and refractory status epilepticus represent some of the most complex conditions encountered in the neurological intensive care unit. Challenges in management are common as treatment options become limited and prolonged hospital courses are accompanied by complications and worsening patient outcomes. Antiepileptic drug treatments have become increasingly complex. Rational polytherapy should consider the pharmacodynamics and kinetics of medications. When seizures cannot be controlled with medical therapy, alternative treatments, including early surgical evaluation can be considered; however, evidence is limited. This review provides a brief overview of status epilepticus, and a recent update on the management of refractory status epilepticus based on evidence from the literature, evidence-based guidelines, and experiences at our institution.

Citations

Citations to this article as recorded by  
  • Provider Experience With the Use of Ketamine for Refractory Status Epilepticus
    Gabriela Tantillo, Nicole Davis, Justin Granstein, Ji Yeoun Yoo, Parul Agarwal, Kaitlin Reilly, Alexandra Reynolds, Gina Kayal, John Liang, Nathalie Jetté
    Clinical Neuropharmacology.2024; 47(2): 37.     CrossRef
  • Proanthocyanidin from Vitis vinifera attenuates memory impairment due to convulsive status epilepticus
    Opeyemi Samson Osuntokun, Gbola Olayiwola, Damilare Adedayo Adekomi, Ibukun Peter Oyeyipo, Abiodun Oladele Ayoka
    Epilepsy & Behavior.2021; 124: 108333.     CrossRef
  • Effect of Sodium Valproate Treatment on the Cardiac Index in New Cases with Status Epilepticus
    Mohammad Radgoudarzi, Mohammad Vafaee-Shahi, Fatemeh Naderi
    The Open Neurology Journal.2021; 15(1): 59.     CrossRef
  • Electroconvulsive Therapy in Super Refractory Status Epilepticus: Case Series with a Defined Protocol
    Beatriz García-López, Ana Isabel Gómez-Menéndez, Fernando Vázquez-Sánchez, Eva Pérez-Cabo, Francisco Isidro-Mesas, Arturo Zabalegui-Pérez, Ignacio Muñoz-Siscart, María Carmen Lloria-Gil, Raúl Soto-Cámara, Jerónimo J. González-Bernal, Josefa González-Santo
    International Journal of Environmental Research and Public Health.2020; 17(11): 4023.     CrossRef
  • Correlation of serum S100B levels with brain magnetic resonance imaging abnormalities in children with status epilepticus
    Prastiya Indra Gunawan, Darto Saharso, Dian Purnama Sari
    Korean Journal of Pediatrics.2019; 62(7): 281.     CrossRef
  • Clinico-Etiological Profile of Pediatric Refractory Status Epilepticus at a Public Hospital in India
    KC Sadik, Devendra Mishra, Monica Juneja, Urmila Jhamb
    Journal of Epilepsy Research.2019; 9(1): 36.     CrossRef

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