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Korean J Crit Care Med > Volume 28(2); 2013 > Article
Korean Journal of Critical Care Medicine 2013;28(2): 156-159. doi: https://doi.org/10.4266/kjccm.2013.28.2.156
외과계 중환자실 환자에서 티아민 결핍에 의해 발생한 습성 각기병과 베르니케 뇌병증
연세대학교 의과대학 외과학교실
Experiences of Wet Beriberi and Wernicke's Encephalopathy Caused by Thiamine Deficiency in Critically Ill Patients
Ji Young Jang, Hongjin Shim, Jae Gil Lee
Department of Surgery, Yonsei University College of Medicine, Seoul, Korea. jakii@yuhs.ac
Wet beriberi and Wernicke's encephalopathy (WE) are caused by thiamine deficiency and are potentially lethal and serious diseases. Thiamine deficiency occurs mainly due to poor oral intake or inadequate provision of thiamine in enteral or parenteral nutrition therapy. We report cases of wet beriberi and WE that developed after surgery in a surgical intensive care unit. The first patient, who was diagnosed with wet beriberi, underwent right total mastectomy and radical subtotal gastrectomy, simultaneously. The second was diagnosed with irreversible WE, respectively, due to long-term malnutrition. In both cases, intravenous replacement of thiamine was initiated after the admission to the surgical intensive care unit. However, comatose mentality of the second patient did not improve. As a result, we conclude that, if a patient's clinical feature is suspected to be thiamine deficiency, prompt intravenous thiamine replacement is needed.
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