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HOME > Acute Crit Care > Volume 25(4); 2010 > Article
Case Report Diffuse Alveolar Hemorrhage Subsequently Developed after Recovery from Severe Acute Lung Injury Caused by H1N1 Influenza Infection: A Case Report
Kyung Ah Lim, Ye Rym Lee, Soo Yeon Cho, Du Hwan Choe, Jae Soo Koh, Byoung Jun Lee, Hye Ryoun Kim, Cheol Hyeon Kim, Jae Cheol Lee

1Department of Internal Medicine, Korea Cancer Center Hospital, Seoul, Korea.
2Department of Radiology, Korea Cancer Center Hospital, Seoul, Korea.
3Department of Pathology, Korea Cancer Center Hospital, Seoul, Korea.
4Department of Internal Medicine, Bohun Hospital, Seoul, Korea.
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Severe acute lung injury (ALI), leading to respiratory failure caused by H1N1 infection, developed in a 34-year-old man during a work-up for non-small cell lung cancer. Although he fully recovered through instant treatment with oseltamivir, mechanical ventilation was required again, 7 days later, due to subsequent diffuse alveolar hemorrhage (DAH). Finally, his condition improved and he was able to move out of the intensive care unit. However, multiple pulmonary metastatic nodules appeared over a period of one month, suggesting the aggressive nature of lung cancer. Although he was discharged after chemotherapy, his prognosis seemed poor, considering the rapidity of growth of the lung cancer. It is important to recognize that DAH can occur after acute lung injury caused by influenza virus.

ACC : Acute and Critical Care