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Korean J Crit Care Med > Volume 25(1); 2010 > Article
Korean Journal of Critical Care Medicine 2010;25(1): 33-36. doi: https://doi.org/10.4266/kjccm.2010.25.1.33
메스암페타민(Methamphetamine) 급성 중독으로 발생한 다발성 장기기능부전 및 사지마비 -증례 보고-
경희대학교 의과대학 응급의학교실
Multiple Organ Dysfunction Syndrome and Quadriplegia due to Acute Methamphetamine Intoxication: A Case Report
Oh Young Kwon, Jong Seok Lee, Han Sung Choi, Hoon Pyo Hong, Young Gwan Ko
Department of Emergency Medicine, College of Medicine, Kyung Hee University, Seoul, Korea. ygko@khu.ac.kr
Methamphetamine (MA) is an extremely addictive central nervous system stimulant. MA abuse has increased during the past three decades in Korea because it is cheap relatively and easily produced. Acute toxicity can occur via nasal insufflation, intravenous administration and ingestion of liquid formulations. The clinical manifestations include hypertension, tachycardia, hyperthermia, an altered mentality and seizure. Severe complications can occur such as pulmonary edema, rhabdomyolysis, disseminated intravascular coagulation and multiple organ dysfunction syndrome. This case report describes a previously healthy 40-year-old woman who presented to an emergency department with complaints of hyperthermia, an altered mentality and vomiting. This patient was diagnosed as acute MA intoxication by urine toxicology screening, and she showed a variety of clinical manifestations and complications. Physicians should suspect MA intoxication if a patient shows an unknown fever, an altered mentality and hypertension, and they should carefully manage these patients in the ICU.
Key Words: methamphetamine; multiple organ dysfunction syndrome; rhabdomyolysis
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